PhD / Research · Ethics and Research Integrity

Conflicts of interest

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Conflict of interest — on-site reading

This reference extract addresses Conflict of interest, a related subject. It does not cover every part of Conflicts of interest.. The article introduction is reproduced here, so you do not need to leave MedAtlas to read it. It may not match the latest official medical guidance.

A conflict of interest (COI) is a situation in which a person or organization is involved in multiple interests, financial or otherwise, and serving one interest could involve working against another. Typically, this relates to situations in which the personal interest of an individual or organization might adversely affect a duty owed to make decisions for the benefit of a third party.
An "interest" is a commitment, obligation, duty or goal associated with a specific social role or practice. By definition, a "conflict of interest" occurs if, within a particular decision-making context, an individual is subject to two coexisting interests that are in direct conflict with each other ("competing interests"). This is important because under these circumstances, the decision-making process can be disrupted or compromised, affecting the integrity or reliability of the outcomes.
Typically, a conflict of interest arises when an individual occupies two social roles simultaneously, generating opposing benefits or loyalties. The interests involved can be pecuniary or non-pecuniary. The existence of such conflicts is an objective fact, not a state of mind, and does not in itself indicate any lapse or moral error. However, especially where a decision is being taken in a fiduciary context, it is important that the contending interests are clearly identified and the process for separating them is rigorously established. Typically, this will involve the conflicted individual either giving up one of the conflicting roles or recusing themselves from the particular decision-making process.
The presence of a conflict of interest is independent of the occurrence of inappropriateness. Therefore, a conflict of interest can be discovered and voluntarily defused before any corruption occurs. A conflict of interest exists if the circumstances are reasonably believed (based on past experience and objective evidence) to create a risk that a decision may be unduly influenced by other, secondary interests, and not on whether a particular individual is actually influenced by a secondary interest.
A widely used definition is: "A conflict of interest is a set of circumstances that creates a risk that professional judgment or actions regarding a primary interest will be unduly influenced by a secondary interest." Primary interest refers to the principal goals of the profession or activity, such as the protection of clients, the health of patients, the integrity of research, and the duties of public officers. Secondary interest includes personal benefit and is not limited to only financial gain but also such motives as the desire for professional advancement, or the wish to do favors for family and friends. These secondary interests are not treated as wrong in and of themselves, but become objectionable when they are believed to have greater weight than the primary interests. Conflict of interest rules in the public sphere mainly focus on financial relationships because they are relatively objective, fungible, and quantifiable, and they usually involve the political, legal, and medical fields.

A conflict of interest is a set of conditions in which professional judgment concerning a primary interest (such as a patient's welfare or the validity of research) tends to be unduly influenced by a secondary interest (such as financial gain). Conflict-of-interest rules [...] regulate the disclosure and avoidance of these conditions.

How this connects to Ethics and Research Integrity

Research integrity requires transparent methods, ethical approval where applicable, valid informed consent and protection of confidential data. Authors must report limitations and distinguish a planned analysis from post-hoc findings; a checklist does not remove conflicts of interest or flawed design.

Text credit: Wikipedia contributors, “Conflict of interest”, original article · authors & revision history · CC BY-SA 4.0. Unmodified opening extract, accessed 24 September 2026. This Wikipedia-derived section is provided under CC BY-SA 4.0; the independent MedAtlas notes and design are separate works.

On-site diagram

Conflicts of interest · visual study map

Scalable vector illustration. Labeled conceptual map, not a precise anatomical, histological or diagnostic image.
TOPIC LEARNING MAP · NOT AN ANATOMICAL PLATE01 · BackgroundA conflict of interest (COI) is asituation in which a person ororganization is involved in multiple…02 · Main conceptTypically, this relates to situations inwhich the personal interest of anindividual or organization might…03 · Related processAn "interest" is a commitment,obligation, duty or goal associated witha specific social role or practice.04 · Study connectionBy definition, a "conflict of interest"occurs if, within a particulardecision-making context, an…Conflicts of interestRead the full text below the visual · all reading is on this website

The wording in this learning map is adapted from the attributed Wikipedia background section below (CC BY-SA 4.0).

Study foundation 01

What the underlying subject studies

Biomedical research begins with a focused, ethically valid question. Define the study population, variables, measurements and decision-relevant uncertainty before selecting a method.

Study foundation 02

How mechanisms and evidence connect

Compare alternative study designs and account for sampling, confounding, bias, imprecision, missing data and the limits of causal inference. Sound statistical analysis cannot repair invalid measurements or unethical recruitment.

Study foundation 03

How to develop a sound explanation

Doctoral-level mastery involves reading primary methods, reproducing calculations, writing transparent protocols and defending the assumptions behind each conclusion. University-specific courses and laboratory competencies differ.

References and verification (optional)

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