MBBS · General Medicine

Approach to chest pain

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Chest pain — on-site reading

This reference extract addresses Chest pain, a related subject. It does not cover every part of Approach to chest pain.. The article introduction is reproduced here, so you do not need to leave MedAtlas to read it. It may not match the latest official medical guidance.

Chest pain is pain or discomfort in the chest, typically the front of the chest. It may be described as sharp, dull, pressure, heaviness or squeezing. Associated symptoms may include pain in the shoulder, arm, upper abdomen, or jaw, along with nausea, sweating, or shortness of breath. It can be divided into heart-related and non-heart-related pain. Pain due to insufficient blood flow to the heart is also called angina pectoris. Those with diabetes or the elderly may have less clear symptoms.
Serious and relatively common causes include acute coronary syndrome such as a heart attack (31%), pulmonary embolism (2%), pneumothorax, pericarditis (4%), aortic dissection (1%) and esophageal rupture. Other common causes include gastroesophageal reflux disease (30%), muscle or skeletal pain (28%), pneumonia (2%), shingles (0.5%), pleuritis, traumatic and anxiety disorders. Determining the cause of chest pain is based on a person's medical history, a physical exam and other medical tests. About 3% of heart attacks, however, are initially missed.
Management of chest pain is based on the underlying cause. Initial treatment often includes the medications aspirin and nitroglycerin. The response to treatment does not usually indicate whether the pain is heart-related. When the cause is unclear, the person may be referred for further evaluation.
Chest pain represents about 5% of presenting problems to the emergency room. In the United States, about 8 million people go to the emergency department with chest pain a year. Of these, about 60% are admitted to either the hospital or an observation unit. The cost of emergency visits for chest pain in the United States is more than US$8 billion per year. Chest pain accounts for about 0.5% of visits by children to the emergency department.

How this connects to General Medicine

Molecular investigation links DNA variation and gene regulation to RNA, proteins and cellular function. Assays measure selected molecular features with finite sensitivity and specificity; a detected variant or transcript does not automatically establish biological causation or a clinical diagnosis.

Text credit: Wikipedia contributors, “Chest pain”, original article · authors & revision history · CC BY-SA 4.0. Unmodified opening extract, accessed 24 September 2026. This Wikipedia-derived section is provided under CC BY-SA 4.0; the independent MedAtlas notes and design are separate works.

On-site diagram

Approach to chest pain · visual study map

Scalable vector illustration. Labeled conceptual map, not a precise anatomical, histological or diagnostic image.
TOPIC LEARNING MAP · NOT AN ANATOMICAL PLATE01 · BackgroundChest pain is pain or discomfort in thechest, typically the front of the chest.02 · Main conceptIt may be described as sharp, dull,pressure, heaviness or squeezing.03 · Related processAssociated symptoms may include pain inthe shoulder, arm, upper abdomen, orjaw, along with nausea,…04 · Study connectionIt can be divided into heart-related andnon-heart-related pain.Approach to chest painRead the full text below the visual · all reading is on this website

The wording in this learning map is adapted from the attributed Wikipedia background section below (CC BY-SA 4.0).

Study foundation 01

What the underlying subject studies

Internal medicine integrates the patient history, examination and selected investigations to explain symptoms across interacting organ systems. A diagnosis is a testable clinical hypothesis, not a result inferred from one symptom or diagram.

Study foundation 02

How mechanisms and evidence connect

Build a mechanistic differential by distinguishing structural, infectious, inflammatory, metabolic, genetic, vascular and medication-related processes as relevant. Consider time course, comorbidities and warning findings.

Study foundation 03

How to develop a sound explanation

For revision, connect normal physiology to possible dysfunction, characteristic patterns and the tests that may discriminate between alternatives. Actual diagnosis and therapy must follow current supervised clinical practice.

References and verification (optional)

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