PhD / Research · Research Methodology

Study design selection

Begin with a precise research question, define the target population and outcome, then choose a study design that answers the question ethically and with feasible data.

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Study designs: where do you start?

Original conceptual SVG · scalable
Research questionpopulation · outcome · timeDesign selectionObservationalexposure not assignedRandomized trialintervention assignedEvidence synthesissystematic reviewEvery design still needs ethical approval, valid measurements and bias assessment

A simplified decision map; study ethics, temporal sequence, feasibility and bias safeguards before selecting a design.

Concept 01

Define the question

Use a structured question such as population, exposure or intervention, comparator, outcome and time frame when appropriate. Specify a single primary outcome before collecting data.

Concept 02

Match design to goal

Descriptive studies characterize populations; cohorts establish temporal ordering; case–control designs are efficient for some rare outcomes; randomized trials compare assigned interventions.

Concept 03

Predefine bias safeguards

Specify sampling, eligibility, missing-data strategy, confounders, ethical approval, preregistration where applicable and a reproducible analysis plan.

Education / safety note: Do not infer causal effects solely from an observed association. Doctoral curricula, coursework credits and examination rules are university- and discipline-specific.

Reference and next reading

Explore the original curriculum and publisher-hosted resources for full-depth reading; this note is an original schematic introduction, not an exhaustive chapter.

Official / publisher source: ICMR biomedical research ethics guidelines ↗Official / publisher source: ICMR biomedical research ethics guidelines ↗Official / publisher source: PubMed ↗