MBBS · Physiology

Gas exchange and transport

Gas transport depends on ventilation, diffusion, perfusion and hemoglobin binding. Oxygen and carbon dioxide follow partial-pressure gradients between alveoli, blood and tissues.

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Gas exchange and transport — learning map

Original conceptual SVG · scalable
LABELED RELATIONSHIP MAP · SCHEMATIC, NOT TO SCALEAlveolar diffusionpartial-pressure gradientOxygen carriagehemoglobin dominantCarbon dioxide carriagethree major formsV/Q matchingairflow and blood flowGas exchange and transportKEY RELATIONSHIPS

Original schematic relationship map for this topic; relationships are organized for study, not intended as an anatomical depiction or a diagnostic algorithm.

Concept 01

Alveolar diffusion

Oxygen diffuses toward pulmonary capillary blood; carbon dioxide diffuses into the alveolus. Barrier thickness and surface area influence transfer.

Concept 02

Oxygen carriage

Most arterial oxygen is bound to hemoglobin, with a small dissolved component; oxygen content depends on hemoglobin concentration and saturation.

Concept 03

Carbon dioxide carriage

Carbon dioxide travels dissolved, attached to proteins and mainly as bicarbonate after carbonic-anhydrase-mediated reactions in red cells.

Concept 04

V/Q matching

Ventilation–perfusion mismatch reduces the efficiency of oxygenation even if the lungs continue to receive air and blood.

Education / safety note: Pulse oximetry estimates hemoglobin saturation, not oxygen content or all causes of respiratory failure.

Reference and next reading

Explore the original curriculum and publisher-hosted resources for full-depth reading; this note is an original schematic introduction, not an exhaustive chapter.

Official / publisher source: NMC official CBME Curriculum 2024 and current regulations index ↗Official / publisher source: NCBI Bookshelf ↗Official / publisher source: PubMed ↗