MBBS · Pharmacology

Adverse drug reactions

An adverse drug reaction is an unintended harmful response associated with appropriate drug use. Causality is assessed from chronology, known pharmacology and competing explanations.

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Adverse drug reactions — learning map

Original conceptual SVG · scalable
LABELED RELATIONSHIP MAP · SCHEMATIC, NOT TO SCALEType A reactionsdose-related predictabilityType B reactionsless predictable patternsInteraction and patient factorsvariable vulnerabilityPharmacovigilancedetect and reportAdverse drug reactionsKEY RELATIONSHIPS

Original schematic relationship map for this topic; relationships are organized for study, not intended as an anatomical depiction or a diagnostic algorithm.

Concept 01

Type A reactions

Augmented reactions tend to relate to known pharmacologic effects and exposure; examples include excessive anticoagulant effect under some circumstances.

Concept 02

Type B reactions

Some immunologic and idiosyncratic reactions are not simply extensions of the expected pharmacological effect.

Concept 03

Interaction and patient factors

Kidney or liver impairment, genetics, age, pregnancy and concurrent medicines may change exposure or sensitivity.

Concept 04

Pharmacovigilance

Clinicians document suspected events and report them using appropriate institutional or regulatory systems, allowing aggregated safety signals to be evaluated.

Education / safety note: Serious suspected reactions require immediate professional assessment; do not discontinue essential medicines based solely on an educational diagram.

Reference and next reading

Explore the original curriculum and publisher-hosted resources for full-depth reading; this note is an original schematic introduction, not an exhaustive chapter.

Official / publisher source: NMC official CBME Curriculum 2024 and current regulations index ↗Official / publisher source: NCBI Bookshelf ↗Official / publisher source: PubMed ↗