MBBS · Community Medicine

Study designs

Epidemiologic study designs organize how exposure, outcomes and comparison groups are measured. Study design influences what conclusions the data can support.

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Study designs: where do you start?

Original conceptual SVG · scalable
Research questionpopulation · outcome · timeDesign selectionObservationalexposure not assignedRandomized trialintervention assignedEvidence synthesissystematic reviewEvery design still needs ethical approval, valid measurements and bias assessment

A simplified decision map; study ethics, temporal sequence, feasibility and bias safeguards before selecting a design.

Concept 01

Observational studies

Cross-sectional designs measure exposure and outcome around the same time. Case–control designs begin by selecting outcome groups, then investigate prior exposures. Cohort designs follow exposure groups to compare outcomes.

Concept 02

Experimental designs

Randomized trials allocate interventions by a random process to reduce some forms of confounding; analysis still must address bias, adherence and uncertainty.

Concept 03

Read critically

No design removes all bias. Check sampling, measurement, selection effects, confounding, effect estimates and confidence intervals before interpreting conclusions.

Education / safety note: Association does not automatically establish causation. Ethical and practical constraints often determine the available study design.

Reference and next reading

Explore the original curriculum and publisher-hosted resources for full-depth reading; this note is an original schematic introduction, not an exhaustive chapter.

Official / publisher source: NMC official CBME Curriculum 2024 and current regulations index ↗Official / publisher source: ICMR biomedical research ethics guidelines ↗Official / publisher source: PubMed ↗